TYPE-2 DIABETICS MAY BE ABLE TO GET RID OF INSULIN SHOTS SOON
Diabetes sufferers might soon be able to take pills to treat their condition, rather than inject themselves with insulin, a research by Australian scientists said on Friday.
Research led by the University of Adelaide is testing safer and more effective drugs to treat type-2 diabetes which will reduce side-effects and insulin injections, Xinhua news agency reported.
Two studies published in the Journal of Medicinal Chemistry and BBA-General Subjection on Friday found that new drugs could be more efficient in reducing blood sugar.
Successfully developing new treatments for type-2 diabetes would be considered a major health coup, with insulin injections often proving unsafe and ineffective.
The two new drugs work by targeting a protein receptor known as PPARgamma found in fat tissue throughout the body to lower blood sugar by increasing sensitivity to insulin and changing the metabolism of fat and sugar.
The first study, undertaken in partnership with The Scripps Research Institute in the US, described 14 versions of a drug which worked by partially activating PPARgamma, an outcome which resulted in fewer side effects than full activation.
The second study, in collaboration with South Australia's Flinders University, used X-ray crystallography to demonstrate how a drug, rivoglitazone, binds with the PPARgamma receptor.
Rivoglitazone fully activates PPARgamma but produced fewer side effects than other drugs that activate the same way.
Type-2 diabetes is characterized by a resistance to insulin and subsequent high blood sugar, usually resulting from lifestyle factors like poor diet and lack of exercise.
John Bruning from the University's School of Biological Sciences and Institute for Photonics and Advanced Sensing said developing safer and more efficient drugs is essential.
this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
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Research led by the University of Adelaide is testing safer and more effective drugs to treat type-2 diabetes which will reduce side-effects and insulin injections, Xinhua news agency reported.
Two studies published in the Journal of Medicinal Chemistry and BBA-General Subjection on Friday found that new drugs could be more efficient in reducing blood sugar.
Successfully developing new treatments for type-2 diabetes would be considered a major health coup, with insulin injections often proving unsafe and ineffective.
The two new drugs work by targeting a protein receptor known as PPARgamma found in fat tissue throughout the body to lower blood sugar by increasing sensitivity to insulin and changing the metabolism of fat and sugar.
The first study, undertaken in partnership with The Scripps Research Institute in the US, described 14 versions of a drug which worked by partially activating PPARgamma, an outcome which resulted in fewer side effects than full activation.
The second study, in collaboration with South Australia's Flinders University, used X-ray crystallography to demonstrate how a drug, rivoglitazone, binds with the PPARgamma receptor.
Rivoglitazone fully activates PPARgamma but produced fewer side effects than other drugs that activate the same way.
Type-2 diabetes is characterized by a resistance to insulin and subsequent high blood sugar, usually resulting from lifestyle factors like poor diet and lack of exercise.
John Bruning from the University's School of Biological Sciences and Institute for Photonics and Advanced Sensing said developing safer and more efficient drugs is essential.
this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
https://gscrochetdesigns.blogspot.com. one can see my crochet creations
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement
Diabetes
sufferers might soon be able to take pills to treat their condition,
rather than inject themselves with insulin, a research by Australian
scientists said on Friday.
Research led by the University of Adelaide is testing safer and more effective drugs to treat type-2 diabetes which will reduce side-effects and insulin injections, Xinhua news agency reported.
Two studies published in the Journal of Medicinal Chemistry and BBA-General Subjection on Friday found tha ..
Research led by the University of Adelaide is testing safer and more effective drugs to treat type-2 diabetes which will reduce side-effects and insulin injections, Xinhua news agency reported.
Two studies published in the Journal of Medicinal Chemistry and BBA-General Subjection on Friday found tha ..
Labels: changes, fat and sugar, increases, insulin injection, metabolism, new effective drug, PPARgamma, protein receptor, reduce, sensitivity, side-effects, targets, tissues, type 2 diabetes
posted by G S Iyer at 9:36 AM
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