Type 2 Diabetes Responsible For Brain Atrophy.

According to a latest research carried out by the University of Pennsylvania, Type 2 diabetes can make a person prone to brain atrophy. It is, however, the first such study linking diabetes to a change in the brain size.


For the study, MRI scans were used to look at the brains of 614 people with Type 2 diabetes. The volunteers had diabetes for 10 years on average.

According to a Dr., diabetes is associated with an increased risk for stroke and dementia. Another expert noted that brain loss may lead to an earlier onset of dementia. Diabetes affects the brain in two ways- damage to blood vessels and brain-cell degeneration like in case of Alzheimer’s disease. 

Researchers also looked at patients who received their diagnosis 15 years ago or more and they had less gray matter compared to those who had been diagnosed four years back or less.  They also found that while on average, most humans lose about 1.5 to 2 cc of brain volume per year, the diabetic patients lost about twice as much. This study also suggests that chronic high levels of insulin and sugar are toxic to brain cells.

It is highly possible that abnormal glucose metabolism in the body could lead to more free radical formation, which increases inflammation, thus quickening the demise of older brain cells. The team will, however, test whether aggressive treatment to lower their blood-sugar levels can have an effect on the brain loss.

But, what still lies shrouded in obscurity is whether treating diabetes will prevent or slow down brain shrinkage.

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