Moderate cholesterol intake not associated with risk of stroke
Consuming up to one egg
per day or moderately high intake of dietary cholesterol does not
increase the risk of stroke, according to a study. Furthermore, no association was found in carriers of
the APOE4 phenotype, which affects cholesterol metabolism.
Findings
from earlier studies addressing the association of dietary cholesterol
or egg intake with the risk of stroke have been contradictory. Some
studies have found an association between high dietary cholesterol
intake and an increased risk of stroke, while others have associated the
consumption of eggs, which are high in cholesterol, with a reduced risk
of stroke.
The dietary habits of
1,950 men aged between 42 and 60 years with no baseline diagnosis of
cardiovascular disease were assessed at the onset the Kuopio Ischaemic
Heart Disease Risk Factor Study, KIHD, in 1984-1989. APOE phenotype data were available for 1,015 of the
men participating in the study. Of those, 32 per cent were known
carriers of APOE4.
During a follow-up of
21 years, 217 men were diagnosed with a stroke. The study found that
neither dietary cholesterol nor egg consumption was associated with the
risk of stroke - not even in carriers of APOE4.
The findings suggested
that moderate cholesterol intake or daily egg consumption are not
associated with the risk of stroke, even in persons who are genetically
predisposed to a greater effect of dietary cholesterol on serum
cholesterol levels.
In the highest control group, the study participants
had an average daily dietary cholesterol intake of 520 mg and they
consumed an average of one egg per day, which means that the findings
cannot be generalised beyond these levels. One egg contains
approximately 200 mg of cholesterol. In this study, about a fourth of
the total dietary cholesterol consumed came from eggs.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE
HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.
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Labels: APOE4 phenotype, cardiovascular diseases, Cholesterol, Kuopio Ischaemic Heart Disease Risk Factor (KIHD), metabolism, moderate, no risk of stroke
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