Novel therapy promises prostate cancer treatment
A new gene therapy could have the potential to treat prostate cancer
that causes 300,000 deaths worldwide each year, a new study said after
it halted the majority of tumours in laboratory models.
The 'seek-and-destroy' gene therapeutic system was used against two types of a prostate tumour and more than half of them vanished over a period of one month.
However, the therapy is currently in limited use due to lack of delivery systems that can selectively deliver the genes to the tumours without adverse side effects to healthy tissues.
The 'seek-and-destroy' nanomedicine linked to an iron-carrying protein called lactoferrin was developed and the study focused on two prostate cancer cell lines -- PC-3 and DU145.
The intravenous administration of the nanomedicine treatment resulted in the complete disappearance of 70 per cent of the PC-3 tumours and half of the DU145 prostate tumours over one month, revealed the findings published in the journal.
"Although some treatments, including chemotherapy and radiotherapy, can be effective against localised tumours, there is still no effective treatment for patients whose cancer recurs or spreads.
"This means that new therapeutic approaches are urgently needed for these patients," said a Senior Lecturer and researcher. Prostate cancer is the fourth most widespread cancer in the world.
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The 'seek-and-destroy' gene therapeutic system was used against two types of a prostate tumour and more than half of them vanished over a period of one month.
However, the therapy is currently in limited use due to lack of delivery systems that can selectively deliver the genes to the tumours without adverse side effects to healthy tissues.
The 'seek-and-destroy' nanomedicine linked to an iron-carrying protein called lactoferrin was developed and the study focused on two prostate cancer cell lines -- PC-3 and DU145.
The intravenous administration of the nanomedicine treatment resulted in the complete disappearance of 70 per cent of the PC-3 tumours and half of the DU145 prostate tumours over one month, revealed the findings published in the journal.
"Although some treatments, including chemotherapy and radiotherapy, can be effective against localised tumours, there is still no effective treatment for patients whose cancer recurs or spreads.
"This means that new therapeutic approaches are urgently needed for these patients," said a Senior Lecturer and researcher. Prostate cancer is the fourth most widespread cancer in the world.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES. PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG- https://gseasyrecipes.blogspot.com/
FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG- https:// kneereplacement-stickclub.blogspot.com/
FOR CROCHET DESIGNS https://gscrochetdesigns.blogspot.com
Labels: cancer cells-PC3 and DU145, deliver, genes, localised, nanomedicine, new gene therapy, no adverse effects, prostate cancers, seek and destroy, selectively, therapeutic, tumour, vanished
posted by G S Iyer at 7:53 AM
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