Thursday, March 29, 2018

Aggressive lowering of BP may up risk of CHD in diabetes

Aggressive lowering of blood pressure may be associated with increased risk of coronary heart disease (CHD) in black or white patients with diabetes, according to research.

The scientists conducted a prospective cohort study from 2000 to 2009 involving 17,536 African-American and 12,618 Caucasian patients with diabetes. The association of blood pressure with CHD risk was analyzed.

The researchers identified 7,620 cases of incident CHD at a mean follow-up of 6.0 years. After adjustment for multiple variables, the hazard ratios of CHD associated with BP at baseline in blacks with diabetes were 1.73 for <110 0.95="" 0.99="" 1.00="" 1.04="" 1.06="" 1.08="" 1.11="" 1.16="" 1.27="" 1.60="" 110-119="" 120-129="" 130-139="" 140-159="" 60="" a="" aged="" an="" and="" association="" at="" baseline="" between="" black="" blood="" both="" bp="" changed="" chd="" diabetes.="" diabetes="" diastolic="" during="" follow-up="" font="" for="" found="" hazard="" hg="" in="" inverse="" isolated="" levels="" mm="" multivariable-adjusted="" of="" older="" or="" patients="" pressure="" ratios="" relationship.="" respectively.="" risk="" systolic="" the="" these="" this="" to="" u-shaped="" was="" were="" white="" whites="" who="" with="" years="">

"In summary, in this large hospital-based cohort study, we found that aggressive blood pressure (i.e., systolic BP <120 2="" african-american="" among="" an="" and="" associated="" authors="" both="" bp="" chd="" diabetes="" diabetic="" diastolic="" elder="" even="" font="" for="" group="" harm="" hg="" higher.="" increased="" is="" mm="" of="" or="" patients="" risk="" the="" type="" urthermore="" white="" with="" write.="">

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