Urinary Tract Infections Detects in an Hour with new device
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A team of researchers have developed a new device
that dramatically cuts the time to detect bacterial species that cause
urinary tract infections -- a major cause of sepsis.
In the pilot study, researchers were able to identify E. coli and Enterococcus faecalis -- two species known to cause urinary tract infections -- within 70 minutes, directly from patients' urine samples.
In the pilot study, researchers were able to identify E. coli and Enterococcus faecalis -- two species known to cause urinary tract infections -- within 70 minutes, directly from patients' urine samples.
The speedy diagnosis marks a tremendous reduction in the wait time compared to the lengthy lag -- often 24 hours or more -- associated with methods routinely used to identify bacteria and diagnose urinary tract infections today.
The lab-on-a-disc platform uses Raman microscopy, a modern optical detection method.
This medical diagnostics device is designed to harness centrifugal force to capture the tiny bacteria directly from patients' samples of bodily fluids...in this case, urine, the study said.
The work involves extremely small sample sizes, on the scale of a small raindrop, so the device needed to be a microfluidic one.
The device works by loading a few microliters of a patient's urine sample into a tiny chip, which is then rotated with a high angular velocity so that any bacteria is guided by centrifugal force through microfluidic channels to a small chamber where it is collected for optical investigation.
Labels: bacterial, E.coli, microfuidic channels, sepsis, urinary tract infection
posted by G S Iyer at 10:40 AM
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