Sunday, January 05, 2020

Blindness in AMD patients: Study says brain can integrate artificial and natural vision correctly

A new research  has found that the brain knows how to integrate natural and artificial vision while maintaining information processing that is important for the vision which can help in better treatment for age-related macular degeneration (AMD).

The study mentioned that AMD in the West causes blindness in millions of people. In the Western world, it is the most common cause of serious vision loss for those aged 50 and over and is growing with age. Although no remedy is available for AMD, recent significant advances in artificial retina implants may contribute to effective treatment.

Locate inside the eye, the retina contains light receptors ( photo-receptors) that absorb light. Information is then processed and transmitted to the brain.

The macula, the central area of the retina, processes most of the information that reaches the brain from the eye. enabling one to see while reading and driving, facial recognition, and any other activity that required accurate vision.

In the peripheral retina, the area of the retina outside the macula that assist mainly with spatial judgement, vision is 10-20 times less precise.

in AMD, precise vision is impaired due to damage to the centre of the retina, while peripheral vision remains normal.

When there is damage to the photo-receptor layers in the retina, an artificial retina may be implanted. Activating these electrodes results in electrical stimulation of the remaining retina cells and results in the visual restoration, albeit partially.

AMD patients implanted with an artificial retina possess a combination of artificial central vision and normal peripheral vision. This combination of artificial and natural vision is important to study in order to understand how to help the blind.

One of the key issues here is whether the brain can integrate artificial and natural vision correctly.
One of the researchers has used a unique projection system that stimulated either natural vision, artistic vision or a combination of natural and artificial vision and at the same time records cortical responses in rodents implanted with a subretinal implant.

The implant is made up of dozens of small solar cells and electrodes developed at Standford Uni.
These ground breaking findings have implications on better vision restore for retinal prosthetic implanted in AMD patients and help the theory of incorporation of prosthetic and natural vision into the brain.
The findings can also have an impact on future brain-machine interface systems where artificial and natural procedures co-exist, said the Prof.

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