Poor nutrition during pregnancy may advance menopause

While it is known that inadequate nutrition during fetal development can cause diabetes and heart disease, a new study warns that it could also lead to early menopause at age younger than 45. Prenatal malnutrition was also associated with a higher risk of premature ovarian failure. Natural menopause is a milestone of ovarian aging that results in the end of a woman's reproductive years.

Conversely, an early menopause is associated with increased risk of heart disease, osteoporosis, depression, and memory changes and changes in vaginal and sexual health, according to researchers. "The findings showed that food deprivation during early fetal life affects how long the future ovaries function," said a researcher.. 

Although several studies have investigated the association between malnutrition exposure in early life and risk of various metabolic diseases in adulthood, the association with reproductive ageing was not evaluated.

This new study, involved nearly 2,900 Chinese women and specifically sought to address the effect of early life exposure to malnutrition on age at menopause.

It has already been documented that the development of the hypothalamic-pituitary-gonadal axis during the fetal stage plays a critical role in adulthood reproductive health, the researchers said. 

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