Tuesday, December 19, 2017

Gold nanoparticles could help combat all deadly viruses

Researchers have developed gold nano-particles that can potentially "trick" viruses into thinking they are invading a human cell and then destroy them -- a finding that would help develop a single drug to combat viruses that cause diseases such as HIV, dengue, papillomavirus, herpes and Ebola, all at the same time.

Viruses infect human bodies by binding to cells. 

Once injected in the body, these nano-particles imitate human cells and "trick" the viruses. 

When the viruses bind to the nano-particles, to infect them, the resulting pressure deforms the virus and opens it, rendering it harmless. Unlike other treatments, the use of pressure is non-toxic.

"Viruses replicate within cells, and it is very difficult to find a chemical substance that attacks viruses without harming the host cells," said a researcher.

"But until now, that's been the only known approach attempted permanently to damage viruses," he added.

However, the gold nano-particles are harmless to humans, and they imitate human cell receptors -- specifically the ones viruses seek for their own attachment to cells. 

The novel nano-particles is unique in that it achieves permanent damage to the viral integrity without damaging living cells, the researchers said.

Moreover, the broad-spectrum antiviral drugs would also help curb the antimicrobial resistance resulting from the over-prescription of antibiotics, revealed the study.

"Doctors often prescribe antibiotics in response to viral infections, since there is no other drug available. But antibiotics are only effective against bacteria, and this blanket use fosters the development of virus mutations and a build-up of resistance in humans," the researcher said.
 

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