Chronic migraine cases are amplified by jawbone disorder

In a new study, a group of researchers have found that the more frequent the migraine attacks, the more severe will be the so-called temporomandibular disorder. 

The temporomandibular joint acts like a sliding hinge connecting the jawbone to the skull, therefore the disorder's symptoms includes difficulty chewing and joint tension.

The first author of the study said, “Our study shows that patients with chronic migraine, meaning attacks occurring on more than 15 days per month, are three times as likely to report more severe symptoms of TMD than patients with episodic migraine.” 

Previous studies already indicated that migraine is somehow associated with pain in the chewing muscles. 

However, this research was the first to consider the frequency of migraine attacks when analyzing its connection with TMD: eighty-four women in their early to mid-thirties were assessed, being that 21 were chronic migraine patients, 32 had episodic migraine, while 32 with no history of migraine were included as controls. 

Signs and symptoms of TMD were observed in 54 percent of the control participants without migraine, 80 percent of participants with episodic migraine, and 100 percent of those with chronic migraine.

For researcher, central sensitization may explain the association between the frequency of migraine attacks and the severity of TMD.

Researcher noted, “The repetition of migraine attacks may increase sensitivity to pain. Our hypothesis is that migraine acts as a factor that predisposes patients to TMD. On the other hand, TMD can be considered a potential perpetuating factor for migraine because it acts as a constant nociceptive input that contributes to maintaining central sensitization and abnormal pain processes.” 

Nociceptive pain is caused by a painful stimulus on special nerve endings called nociceptors.

Migraine and TMD have very similar pathological mechanisms. Migraine affects 15 percent of the general population, and progression to the chronic form is expected in about 2.5 percent of migraine sufferers. 

On the other hand TMD is stress-related as much as it has to do with muscle overload. Patients display joint symptoms -- such as joint pain, reduced jaw movement, clicking or popping of the temporomandibular joint, but also develop a muscular condition, including muscle pain and fatigue, and/or radiating face and neck pain.

TMD and migraine are comorbidities. However, while people who suffer from migraine are predisposed to have TMD, people with TMD will not necessarily have migraine.

“Migraine patients are more likely to have signs and symptoms of TMD, but the reverse is not true. There are cases of patients with severe TMD who don't present with migraine,” shared the lead researcher for the study and principal investigator for the Project.

The researchers believe that TMD may increase the frequency and severity of migraine attacks, even though it does not directly cause migraine.

“We do know migraine isn't caused by TMD. Migraine is a neurological disease with multifactorial causes, whereas TMD, like cervicalgia -- neck pain -- and other musculoskeletal disorders, is a series of factors that intensify the sensitivity of migraine sufferers. Having TMD may worsen one's migraine attacks in terms of both severity and frequency,” noted author. 

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