Repeated antibiotic exposure in first 2 years of life linked to childhood obesity
A new study conducted by researchers from the US has shown that young
children who are given antibiotics repeatedly are more at risk of
turning obese than those who use fewer drugs.
The JAMA Pediatrics report said that children who
were given four or more courses before turning two were at a 10% higher
risk of childhood obesity.
But the researchers asserted that this does
not show that antibiotics are directly linked to obesity and recommend
children could use them. They added that some more studies should be
done to find out the reasons behind the link.
The study is done by the researchers from the
University of Pennsylvania and Bloomberg School of Public Health. For
the study, the researchers reviewed the health records of more than
64,500 American children between 2001 and 2013.
The researchers followed the children till
they turned five. Almost 70% of the children were prescribed two courses
of antibiotics by the time they were 24 months old.
Prof Charles Bailey at the University of
Pennsylvania, said: "We think after antibiotics some of the normal
bacteria in our gut that are more efficient at nudging our weight in the
right direction may be killed off and bacteria that nudge the
metabolism in the wrong direction may be more active."
He added that the findings of the study show that over prescription of antibiotics could affect the child growth.
Prof Nigel Brown, president of the Society
for General Microbiology in the UK told BBC: "This study adds further
evidence that the use of antibiotics early in life has a role to play in
obesity. While antibiotic use is only one factor that may predispose
children to be obese, the study emphasises the importance of rapid
diagnostic tests that allow precise targeting of antibiotics, which will
kill the disease-causing bacteria and cause minimum disruption to the
normal gut flora."
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Labels: antibiotics, childhood obesity, gut bacteria, young children
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