Antibiotics at early age can reduce immunity
A new study has found that consumption of antibiotics at an early age can reduce long-term immunity.
The new study is done by researchers
from University of British Columbia (UBC). The study was done to help
scientists understand how bacteria are affected by different
antibiotics. It is to be noted that bacteria also play a positive role
in promoting a healthy immune system.
The study showed that taking antibiotics at early stage can increase susceptibility to specific diseases at a later stage.
We know that there are some bacteria living
in our gut and they play a positive role in promoting a healthy immune
system. Sometimes the good bacteria also get killed due to antibiotic
treatments.
"This is the first step to understanding
which bacteria are absolutely necessary to develop a healthy immune
system later in life," said Kelly McNagny, a professor in the Department
of Medical Genetics who led the research along with UBC microbiologist
Brett Finlay.
For the study, the impact of two antibiotics,
vancomycin and streptomycin, were tested on newborn mice. The
researchers found that streptomycin increased susceptibility to a
disease known as hypersensitivity pneumonitis later in life, but
vancomycin did not have any such effect.
The study said that difference in long-term
effects of an antibiotic can be attributed to how they affect the
presence of gut bacteria.
Hypersensitivity pneumonitis is an allergic
disease which affects people involved in farming, sausage-making, and
cleaning hot tubs.
The researchers, however, noted that
antibiotics should be given to infants when needed but they expressed
hope that the findings of the study will help them know which bacteria
make us less susceptible to disease.
This could allow the researchers to boost helpful bacteria by using probiotics.
"Probiotics could be the next big trend in
parenting because once you know which bacteria prevent disease, you can
make sure that children get inoculated with those bacteria," said
McNagny.
The study was published in the Journal of Allergy and Clinical Immunology.
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Labels: antibiotics, early age, hypersensitivity pneumonitis, increases susceptibility to diseases, long term immunity, probiotics, reduces, streptomycin, vancomycin
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