' Clostridia' gut bacteria protect against food allergies
A class of bacteria usually found in the gut of healthy people can be
utilized to cure food allergies in the future, according to U.S.
researchers.
The
researchers at University of Chicago demonstrated a group of gut
bacteria called Clostridia, which can block peanut allergies in mice.
They want to harness the bacteria in a pill
form, or copy their effects with a medicine to treat allergies beginning
with food allergies.
For every one cell that builds up the human
body, there are 10 bacteria living on or in us. The team conducted
experiments on mice brought up in sterile environments and had no
bacteria in their gut.
It must be noted that mice have strong immune
response to peanut - an allergy that can be lethal in some people. The
researchers investigated whether adding different bacteria to the
digestive tract of the animals had any effect.
It was found that only the Clostridia group
of bacteria, which includes some disease causing species such as C.
difficle, can prevent allergic reaction.
The researchers are also trying to look for another option by finding a drug which would have the same effect as the bacteria.
The researchers hope that using bacteria can
assist with desensitisation therapies, which involve giving regular, but
small, doses of the substance stimulating the allergic response until
the immune system becomes used to it.
Previous research has indicated roles for our
microbiome in everything from autism to obesity. Lead researcher Dr.
Cathryn Nagler has said that we should not be surprised how powerful an
effect these viruses, fungi and bacteria can have on our body.
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Labels: clostridia gut bacteria, cures food allergies, desensitization therapies, digestive tract, peanut allergy
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