Friday, May 03, 2013

Progressive coronary artery calcium buildup ups risk of heart attack and death

 A growing build-up of coronary artery calcium puts patients at increased risk of heart attack and death from heart disease, according to a new study.

The study found that patients with increasing accumulations of coronary artery calcium were more than six times more likely to suffer from a heart attack or die from heart disease than patients who didn`t have increasing accumulations.

The study, suggests more frequent monitoring of patients with coronary artery calcium accumulations could help determine the risk of heart attacks and give those patients time to make changes to reduce the risk.

For the study, researchers measured the coronary artery calcium in a diverse group of 6,778 persons aged 45 to 84 years. The participants had no history of coronary heart disease prior to enrolling for the  study.

Researchers found that nearly half of the participants had coronary artery calcium in their initial scans - and most of them continued to accumulate coronary artery calcium, as measured in subsequent CT (computed tomography) scans approximately 2.5 years later.

For those with the greatest increase in coronary artery calcium buildup (300 units or more), the study found a more than six-fold increase in coronary heart disease incidents independent of other risk factors for heart disease.

It is known that coronary artery calcium can be related to heart disease, but this study shows the progression of the accumulation of the calcium in the arteries can be a significant factor in evaluating the risk that a patient may suffer a heart attack in the future.

By conducting serial CT scans,researchers may be able to identify people at high risk of a heart attack and intervene to prevent that heart attack through new therapies, lifestyle changes and other modifications. Further study is needed to determine if more frequent CT scans would be a cost-effective approach to reducing coronary heart disease, the No. 1 cause of death for both men and women in the U.S.


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