Fluoroquinolones antibiotics associated with risk of heart problems
In a new study, researchers have established the link between one of the most commonly prescribed class of antibiotics and heart problems.
In a study, researchers found that current users of fluoroquinolone antibiotics, such as Ciprofloxacin or Cipro, face a 2.4 times greater risk of developing aortic and mitral regurgitation, where the blood back-flows into the heart compared to patients who take amoxicillin, a different type of antibiotic.
The greatest risk is within 30 days of use.
Some physicians favour fluoroquinolones over other antibiotics for their broad spectrum of antibacterial activity and high oral absorption, which is as effective as intravenous or IV, treatment.
You can send patients home with a once-a-day pill, said the lead author of the study.
The class of antibiotics is very convenient, but for the majority of cases, especially community-related infections, they're not really needed. The inappropriate prescribing may cause both antibiotic resistance as well as serious heart problems, added the author.
One of the key objectives of Therapeutic Evaluation Unit is to evaluate different drugs and health technologies to determine whether they enhance the quality of care delivered by our programs or improve patient outcomes, said the researcher.
For the study, researchers analysed data from the U.S. Food and Drug Administration's adverse reporting system. They also analysed a massive private insurance health claims database in the U.S. that captures demographics, drug identification, dose prescribed and treatment duration.
Researchers identified 12,505 cases of valvular regurgitation with 125,020 case-control subjects in a random sample of more than 9 million patients.
They defined current fluoroquinolone exposure as an active prescription or 30 days prior to the adverse event, recent exposure as within days 31-60 , and past exposure as within 61-365 days prior to an incident. They compared fluoroquinolone use with amoxicillin and azithromycin.
The results showed that the risk of aortic and mitral regurgitation, blood back-flow into the heart, is highest with current use, followed by recent use. They saw no increased risk aortic and mitral regurgitation with past use.
this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
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In a study, researchers found that current users of fluoroquinolone antibiotics, such as Ciprofloxacin or Cipro, face a 2.4 times greater risk of developing aortic and mitral regurgitation, where the blood back-flows into the heart compared to patients who take amoxicillin, a different type of antibiotic.
The greatest risk is within 30 days of use.
Some physicians favour fluoroquinolones over other antibiotics for their broad spectrum of antibacterial activity and high oral absorption, which is as effective as intravenous or IV, treatment.
You can send patients home with a once-a-day pill, said the lead author of the study.
The class of antibiotics is very convenient, but for the majority of cases, especially community-related infections, they're not really needed. The inappropriate prescribing may cause both antibiotic resistance as well as serious heart problems, added the author.
One of the key objectives of Therapeutic Evaluation Unit is to evaluate different drugs and health technologies to determine whether they enhance the quality of care delivered by our programs or improve patient outcomes, said the researcher.
For the study, researchers analysed data from the U.S. Food and Drug Administration's adverse reporting system. They also analysed a massive private insurance health claims database in the U.S. that captures demographics, drug identification, dose prescribed and treatment duration.
Researchers identified 12,505 cases of valvular regurgitation with 125,020 case-control subjects in a random sample of more than 9 million patients.
They defined current fluoroquinolone exposure as an active prescription or 30 days prior to the adverse event, recent exposure as within days 31-60 , and past exposure as within 61-365 days prior to an incident. They compared fluoroquinolone use with amoxicillin and azithromycin.
The results showed that the risk of aortic and mitral regurgitation, blood back-flow into the heart, is highest with current use, followed by recent use. They saw no increased risk aortic and mitral regurgitation with past use.
this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
https://gscrochetdesigns.blogspot.com. one can see my crochet creations
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement
Labels: antibiotic resistance, antibiotics, aortic valve, enhance, Fluoroquinolones, heart problems, increases risk of, mitral valve disorder, valvular regurgitation
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