‘Secret handshake’ detected between sperm and uterus

A team of researchers has discovered the making of a “secret handshake” between sperm and the cells lining the uterus that finally let one sperm out of nearly 200 million to make it through and fertilise a single egg, say researchers.

Uterine cells express a receptor that recognizes a glycan molecule on the surface of sperm cells.

It’s possible that this interaction may adjust the female’s immune response and help sperm make it through the leukocytic reaction, said the researchers. The leukocytic reaction is not well understood.

What we do know, explained molecular anthropologist  is that “after crossing the cervix, millions of sperm that arrive in the uterus are faced by a barrage of macrophages and neutrophils”.

This attack by the innate immune system kills a majority of the sperm cells in semen, winnowing hundreds of millions of sperm down to just a few hundred that enter the fallopian tubes.

The defensive response may be beneficial in preventing polyspermy, when an egg is fertilized by more than one sperm and cannot develop.

“It’s somewhat embarrassing how little we can say about what this [interaction] means,” said  a researcher.

Reproduction, he said, “is a very, very delicate tug-of-war at many levels. The fact that there is (also) this immune game going on is completely fascinating.”

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                  https:// kneereplacement-stickclub.blogspot.com/                                                                      FOR CROCHET DESIGNS                                                                                                    

                                https://gscrochetdesigns.blogspot.com