Skipping breakfast disrupts body clock, causes weight gain
Skipping breakfast can disrupt the body's internal clock and cause
weight gain, even if one does not overeat for the rest of the day, a
study has found.
Irregular eating habits such as skipping breakfast are often associated with obesity, type 2 diabetes, hypertension and cardiovascular disease, but the precise impact of meal times on the body's internal clock has been less clear.
Researchers found that the effect of breakfast on the expression of "clock genes" that regulate the post-meal glucose and insulin responses of both healthy individuals and diabetics.
The importance of the body's internal clock and the impact of meal times on the body were the subject of this year's Nobel Prize for Medicine, awarded for the discovery of molecular mechanisms controlling our circadian rhythm.
"Our study shows that breakfast consumption triggers the proper cyclic clock gene expression leading to improved glycaemic control," said the researcher.
"The circadian clock gene not only regulates the circadian changes of glucose metabolism, but also regulates our body weight, blood pressure, endothelial function and atherosclerosis," said the researcher.
"Proper meal timing - such as consuming breakfast before 9:30 am - could lead to an improvement of the entire metabolism of the body, facilitate weight loss, and delay complications associated with type 2 diabetes and other age- related disorders," she said.
For the study, 18 healthy volunteers and 18 obese volunteers with diabetes took part in a test day featuring breakfast and lunch, and in a test day featuring only lunch.
On both days, the researchers conducted blood tests on the participants to measure their postprandial clock gene expression, plasma glucose, insulin and intact glucagon-like peptide-1 (iGLP-1) and dipeptidyl peptidase IV (DPP-IV) plasma activity.
"Our study showed that breakfast consumption triggers the proper cyclic clock gene expression leading to improved glycaemic control," said the researcher.
"In both healthy individuals and in diabetics, breakfast consumption acutely improved the expression of specific clock genes linked to more efficient weight loss, and was associated with improved glucose and insulin levels after lunch," she said.
In contrast, in test days featuring only lunch - when participants skipped breakfast - the clock genes related to weight loss were down regulated, leading to blood sugar spikes and poor insulin responses for the rest of the day, suggesting also that skipping breakfast leads to weight gain even without the incidence of overeating the rest of the day.
"The fact that we can change the gene's expression in just four hours is very impressive," said the researcher.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.
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Irregular eating habits such as skipping breakfast are often associated with obesity, type 2 diabetes, hypertension and cardiovascular disease, but the precise impact of meal times on the body's internal clock has been less clear.
Researchers found that the effect of breakfast on the expression of "clock genes" that regulate the post-meal glucose and insulin responses of both healthy individuals and diabetics.
The importance of the body's internal clock and the impact of meal times on the body were the subject of this year's Nobel Prize for Medicine, awarded for the discovery of molecular mechanisms controlling our circadian rhythm.
"Our study shows that breakfast consumption triggers the proper cyclic clock gene expression leading to improved glycaemic control," said the researcher.
"The circadian clock gene not only regulates the circadian changes of glucose metabolism, but also regulates our body weight, blood pressure, endothelial function and atherosclerosis," said the researcher.
"Proper meal timing - such as consuming breakfast before 9:30 am - could lead to an improvement of the entire metabolism of the body, facilitate weight loss, and delay complications associated with type 2 diabetes and other age- related disorders," she said.
For the study, 18 healthy volunteers and 18 obese volunteers with diabetes took part in a test day featuring breakfast and lunch, and in a test day featuring only lunch.
On both days, the researchers conducted blood tests on the participants to measure their postprandial clock gene expression, plasma glucose, insulin and intact glucagon-like peptide-1 (iGLP-1) and dipeptidyl peptidase IV (DPP-IV) plasma activity.
"Our study showed that breakfast consumption triggers the proper cyclic clock gene expression leading to improved glycaemic control," said the researcher.
"In both healthy individuals and in diabetics, breakfast consumption acutely improved the expression of specific clock genes linked to more efficient weight loss, and was associated with improved glucose and insulin levels after lunch," she said.
In contrast, in test days featuring only lunch - when participants skipped breakfast - the clock genes related to weight loss were down regulated, leading to blood sugar spikes and poor insulin responses for the rest of the day, suggesting also that skipping breakfast leads to weight gain even without the incidence of overeating the rest of the day.
"The fact that we can change the gene's expression in just four hours is very impressive," said the researcher.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.
PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-
HTTP:GSEASYRECIPES.BLOGSPOT.COM/
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Labels: blood sugar spikes, body clock, cardiovascular diseases, circadian rhythm, disrupts, glucose, glycaemic index, hypertension, insulin response, obesity, skipping breakfast, type 2 diabetes, weight gain
posted by G S Iyer at 2:09 AM
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