Steroids ineffective for chest pains in non-asthmatic patients
According to a new research, Oral steroids should not be used for
treating acute lower respiratory tract infection or chest pains in
adults who don't have asthma or other chronic lung diseases, as they do
not reduce the duration or severity of symptoms.
In the study, 398 non-asthmatic adults with acute chest infections but no evidence of pneumonia and not requiring immediate antibiotic treatment were randomly split into two groups.
One group received 40mg of the oral steroid 'prednisolone' for five days (198 participants) and other received an identical placebo over the same time period (200 participants).
The team found there was no reduction in the duration of cough, the main symptom of chest infections, or the severity of the accompanying symptoms between two and four days after treatment (when symptoms are usually at their most severe) in the prednisolone group compared with the placebo group.
The results suggest that steroids are not effective in the treatment of chest infections in non-asthmatic adult patients.
“Chest infections are one of the most common problems in primary care and often treated inappropriately with antibiotics.
Corticosteroids, like prednisolone, are increasingly being used to try to reduce the symptoms of chest infections, but without sufficient evidence,” said the study’s lead author.
Adding, “Our study does not support the continued use of steroids as they do not have a clinically useful effect on symptom duration or severity. We would not recommend their use for this group of patients.”
Study’s co-author added, “Oral and inhaled steroids are known to be highly effective in treating acute asthma as well as infective flares of other long-term lung conditions but need to be used carefully because of the risk of unwanted side effects.” He concluded by saying, “We chose to test the effect of steroids for chest infections as some of the symptoms of chest infections, such as shortness of breath, wheeze and cough with phlegm, overlap with acute asthma. However, we have conclusively demonstrated they are not effective in this group of patients.”
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.
PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-
In the study, 398 non-asthmatic adults with acute chest infections but no evidence of pneumonia and not requiring immediate antibiotic treatment were randomly split into two groups.
One group received 40mg of the oral steroid 'prednisolone' for five days (198 participants) and other received an identical placebo over the same time period (200 participants).
The team found there was no reduction in the duration of cough, the main symptom of chest infections, or the severity of the accompanying symptoms between two and four days after treatment (when symptoms are usually at their most severe) in the prednisolone group compared with the placebo group.
The results suggest that steroids are not effective in the treatment of chest infections in non-asthmatic adult patients.
“Chest infections are one of the most common problems in primary care and often treated inappropriately with antibiotics.
Corticosteroids, like prednisolone, are increasingly being used to try to reduce the symptoms of chest infections, but without sufficient evidence,” said the study’s lead author.
Adding, “Our study does not support the continued use of steroids as they do not have a clinically useful effect on symptom duration or severity. We would not recommend their use for this group of patients.”
Study’s co-author added, “Oral and inhaled steroids are known to be highly effective in treating acute asthma as well as infective flares of other long-term lung conditions but need to be used carefully because of the risk of unwanted side effects.” He concluded by saying, “We chose to test the effect of steroids for chest infections as some of the symptoms of chest infections, such as shortness of breath, wheeze and cough with phlegm, overlap with acute asthma. However, we have conclusively demonstrated they are not effective in this group of patients.”
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.
PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-
HTTP:GSEASYRECIPES.BLOGSPOT.COM/
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Labels: chronic lung disease, ineffective, non-asthmatics, oral steroids
posted by G S Iyer at 10:09 PM
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