Higher childhood vitamin D levels significantly reduce diabetes risk
Getting enough vitamin D during infancy and childhood can reduce
the risk of diabetes in kids genetically predisposed to have the
disease, a study has found.
Researchers examined the association between vitamin D levels in the blood and islet autoimmunity.
Islet autoimmunity, detected by antibodies that appear when the immune system attacks the islet cells in the pancreas that produce insulin, is a precursor to type 1 diabetes.
"For several years there has been controversy among scientists about whether vitamin D lowers the risk of developing of islet autoimmunity and type 1 diabetes," said a researcher.
Type 1 diabetes is a chronic autoimmune disease that is increasing by 3-5 per cent annually worldwide, researchers said.
The disease is now the most common metabolic disorder in children under age 10. In younger children, the number of new cases is particularly high. The risks seem to be greater at higher latitudes, further north from the equator.
Vitamin D represents a candidate protective factor for type 1 diabetes as it regulates the immune system and autoimmunity.
Moreover, vitamin D status varies by latitude. However, associations between vitamin D levels and islet autoimmunity have been inconsistent.
This may be due to different study designs, population variation in vitamin D levels, or a failure to account for the combined effect of exposure and underlying genetic variation in the vitamin D pathway.
The findings are part of study, which looked for triggers and protective factors for type 1 diabetes in 8,676 children with elevated type 1 diabetes risk.
The children were followed with blood samples drawn every three to six months from infancy, to determine the presence of islet autoimmunity, as well as levels of vitamin D.
Researchers compared 376 children who developed islet autoimmunity with 1,041 children who did not.
The study, said that in children with a genetic variant in the vitamin D receptor gene, vitamin D levels in infancy and childhood were lower in those that went on to develop islet autoimmunity compared with those that did not develop autoimmunity.
The study is the first to show that higher childhood vitamin D levels are significantly associated with a decreased risk of IA.
"Since this association does not prove cause-and-effect, we look to future prospective studies to confirm whether a vitamin D intervention can help prevent type 1 diabetes," researcher said.
Researchers examined the association between vitamin D levels in the blood and islet autoimmunity.
Islet autoimmunity, detected by antibodies that appear when the immune system attacks the islet cells in the pancreas that produce insulin, is a precursor to type 1 diabetes.
"For several years there has been controversy among scientists about whether vitamin D lowers the risk of developing of islet autoimmunity and type 1 diabetes," said a researcher.
Type 1 diabetes is a chronic autoimmune disease that is increasing by 3-5 per cent annually worldwide, researchers said.
The disease is now the most common metabolic disorder in children under age 10. In younger children, the number of new cases is particularly high. The risks seem to be greater at higher latitudes, further north from the equator.
Vitamin D represents a candidate protective factor for type 1 diabetes as it regulates the immune system and autoimmunity.
Moreover, vitamin D status varies by latitude. However, associations between vitamin D levels and islet autoimmunity have been inconsistent.
This may be due to different study designs, population variation in vitamin D levels, or a failure to account for the combined effect of exposure and underlying genetic variation in the vitamin D pathway.
The findings are part of study, which looked for triggers and protective factors for type 1 diabetes in 8,676 children with elevated type 1 diabetes risk.
The children were followed with blood samples drawn every three to six months from infancy, to determine the presence of islet autoimmunity, as well as levels of vitamin D.
Researchers compared 376 children who developed islet autoimmunity with 1,041 children who did not.
The study, said that in children with a genetic variant in the vitamin D receptor gene, vitamin D levels in infancy and childhood were lower in those that went on to develop islet autoimmunity compared with those that did not develop autoimmunity.
The study is the first to show that higher childhood vitamin D levels are significantly associated with a decreased risk of IA.
"Since this association does not prove cause-and-effect, we look to future prospective studies to confirm whether a vitamin D intervention can help prevent type 1 diabetes," researcher said.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE
HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.
PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-
HTTP:GSEASYRECIPES.BLOGSPOT.COM/
FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-
FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-
HTTP://KNEE REPLACEMENT-STICK CLUB.BLOGSPOT.COM/
FOR CROCHET DESIGNS
HTTP://MY CROCHET CREATIONS.BLOGSPOT.COM
FOR CROCHET DESIGNS
HTTP://MY CROCHET CREATIONS.BLOGSPOT.COM
Labels: childhood, reduces diabetes risk, type 2 diabetes, Vitamin D
posted by G S Iyer at 9:56 AM
0 Comments:
Post a Comment
<< Home