New Paper-Based Zika Test Can Diagnose Virus in 20 Minutes
Reports state that researchers have developed a new paper-based Zika
virus test which can detect the infection of the virus within 20
minutes. The test reportedly can effectively differentiate the Zika
virus from other mosquito-horned virus like dengue.
Doctors often have difficulty deciphering whether a particular mosquito-borne virus test is positive for Zika or other similar viruses. The resin behind this is the presence of a viral protein called NS1. This protein can be found in the bloodstream of an infected person.
However, many other viruses from the same family, which is called flavi-viruses, have very similar versions of the NS1 and can cause false positives for other viruses. Falvi-vruses reportedly include dengue, the virus which causes yellow fever and even the West Nile virus.
Commenting on the new test for the Zika virus, associate professor said, “It’s important to have a single test that can differentiate between the four serotypes of Dengue and Zika because they co-circulate. They’re spread by the same mosquito.”
In order to reach the findings, the team of researchers exposed mice to Zika and Dengue virus and screened the resulting antibodies in pairs against flavivirus’ version of the NS1 protein. Through this process, the researchers were able to identify the pairs of antibodies that particularly react with one version of the NS1.
The researchers then reportedly used the identified pairs to create five different tests, one for each type of virus. They coated strips of paper with one antibody from each pair, while the second antibody was attached to gold nanoparticles, according to reports.
Although the approach requires five strips per sample to test the presence of each virus, the researchers are currently working on a version through which it would be possible to test all five viruses through one strip.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES. PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-
Doctors often have difficulty deciphering whether a particular mosquito-borne virus test is positive for Zika or other similar viruses. The resin behind this is the presence of a viral protein called NS1. This protein can be found in the bloodstream of an infected person.
However, many other viruses from the same family, which is called flavi-viruses, have very similar versions of the NS1 and can cause false positives for other viruses. Falvi-vruses reportedly include dengue, the virus which causes yellow fever and even the West Nile virus.
Commenting on the new test for the Zika virus, associate professor said, “It’s important to have a single test that can differentiate between the four serotypes of Dengue and Zika because they co-circulate. They’re spread by the same mosquito.”
In order to reach the findings, the team of researchers exposed mice to Zika and Dengue virus and screened the resulting antibodies in pairs against flavivirus’ version of the NS1 protein. Through this process, the researchers were able to identify the pairs of antibodies that particularly react with one version of the NS1.
The researchers then reportedly used the identified pairs to create five different tests, one for each type of virus. They coated strips of paper with one antibody from each pair, while the second antibody was attached to gold nanoparticles, according to reports.
Although the approach requires five strips per sample to test the presence of each virus, the researchers are currently working on a version through which it would be possible to test all five viruses through one strip.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES. PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-
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Labels: diagnosis, flavi-viruses, NS1 protein, viral proteins, Zika virus
posted by G S Iyer at 12:00 AM
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