Diet For Crohn's Disease

A study has shown that a high fat diet could lead to specific changes in gut bacteria that may help fight Crohn's disease.

This is because “good” fats help tackle harmful inflammation.

Since Crohn’s is a type of inflammatory bowel disease, the research might prove a major discovery for sufferers.

There are currently many people who are suffering from the condition where the underlying cause remains unknown.

Symptoms include intestinal swelling, cramping, and diarrhoea.

However, the researchers discovered that a diet of plant-derived "good" fats could reduce bacterial diversity.

Such foods include the coconut oil and cocoa butter that was used in the study, as well as avocados, nuts, salmon and olive oil.

In the study, mice fed fatty diets experienced up to 30 per cent fewer kinds of gut bacteria as their counterparts who were fed a normal diet - this resulted in a very different gut microbial composition. 

Even those fed low concentrations of coconut oil or cocoa butter had less severe small intestine inflammation.
 

The researchers said: “The finding is remarkable because it means that a Crohn's patient could also have a beneficial effect on their gut bacteria and inflammation by only switching the type of fat in their diet.

“Patients would only need to replace a 'bad' fat with a 'good' fat, and eat normal amounts."

Researchers believe the results could lead to new anti-inflammatory probiotics.

This is because they may be able to now identify bacteria to use which can treat patients suffering from inflammatory bowel syndromes. 

The study is one of the first to identify specific changes in gut bacteria - or microbiome - associated with Crohn's disease.

Additionally, it is the first to show how high fat diets can alter gut bacteria to combat inflammation.

A researcher said: “Ongoing studies are now helping us to understand which component of the 'good' and 'bad' fats make the difference in the gut microbes and make mice healthier.

"Ultimately, we aim to identify the 'good' fat-loving microbes for testing as probiotics."



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