Large amounts of E. coli reduced willpower

We don’t know yet whether the brain drives microbial change or vice versa but it’s yet more proof of that the gut-brain connection is real and potent. “The gut microbiome is thought to communicate with the brain in a complex, two-directional way. The microbiome produces neurotransmitters and neurotoxins which access the brain through nerves and the blood circulation. In return the brain controls eating behavior, while nutrients from our diet change the composition of the gut microbiome,” said coauthor Dr Xiaoning Wang from the Institute of Geriatrics of the PLA General Hospital. 

It’s worth flagging that this study did involve quite extreme intermittent fasting (more along the 5:2 lines) but we do know that even gentle forms of IF (ie having 12 hours between dinner and breakfast) can help with energy, blood sugar and inflammation. Clearly, way more research is needed on the topic with far bigger sample sizes, but it’s a promising step in understand the gut-brain axis all the same.