Researchers have developed a novel way to
treat bladder cancer. A team of international researchers achieved 90%
shrinkage of bladder cancers with just one dose of self-propelled
nanorobots.
Bladder cancer, a major worldwide health concern and the fourth most
prevalent malignancy in males, could see a huge increase in treatment
efficiency thanks to this novel approach.
Treatments for non-muscle-invasive bladder
cancer, which accounts for around 75% of cases, involve infusing
immunotherapeutic and/or chemotherapeutic medicines into the bladder
following tumor excision. Despite having favorable survival rates, their
effectiveness is limited, as evidenced by recurrence rates of 30% to
70% after five years. This necessitates regular and costly bladder
monitoring procedures (cystoscopy) and possibly extra treatments for
patients.
Researchers from the Institute for Research in Biomedicine (IRB)
Barcelona, in collaboration with the Institute for Bioengineering of
Catalonia (IBEC), CIC biomaGUNE, and the Autonomous University of
Barcelona (UAB), are working to improve the effectiveness of bladder
cancer treatment. Their coordinated efforts have resulted in the
development of self-propelled nanobots that are strategically designed
to converge on the tumor site and deliver tailored cancer treatment.
The nanorobots, which are essentially small machines, are driven by
urea, a substance found in urine. These nanomachines are made up of a
silica sphere containing many components, including the enzyme urease
and radioactive iodine. Urease combines with urea to push the nanorobot,
while radioactive iodine treats the tumor.
The researchers injected urease-powered
nanobots into the bladders of mouse models with bladder cancer, using
positron emission tomography (PET) scans to illustrate the targeted
accumulation of the bots at the tumor site. Using a stereomicroscope
developed by researchers at the IRB Barcelona, the nanobots were
demonstrated to be capable of efficiently invading tumors. The
administration of iodine-131 by the nanobots at the tumor site led to an
astonishing, nearly 90% reduction in tumor volume.
“With a single dose, we observed a 90%
decrease in tumor volume,” said Samuel Sánchez, one of the study’s
corresponding authors. “This is significantly more efficient than
current treatments, given that patients with this type of tumor
typically have between six and 14 hospital appointments. This
therapeutic approach would increase efficiency by reducing the length of
hospitalizations and the cost of treatment.”
The novel treatment will pave the way for more effective treatment of
bladder cancer in the future. Trying to figure out whether the tumors
will recur after treatment is the next step for the researchers.
The study was published in the journal Nature Nanotechnology.
This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
https://gscrochetdesigns.blogspot.com. one can see my crochet creations
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement
https://cancersupportindia.blogspot.com for infor on cancer and health related topics
https://GSiyers
home remedies.blogspot.com is the latest addition to my blogs. I'm
going to add posts there, do give me your valuable feed back on my
blogs. Thanks a lot, take care, be healthy and be happy.
Labels: admionister- Iodine-131, bladder cancer, chemotherapeutics, cystoscopy, immunotherapeutic, nanorobots, non-muscle invasive bladder cancer, PET scan
0 Comments:
Post a Comment
<< Home