Tuesday, April 02, 2019

Blood test can help diagnose pre-eclampsia

A simple blood test can help diagnose a common but potentially fatal pregnancy complication- pre-eclampsia, finds a study.

During the study, by measuring the concentration of placental growth factor (PIGF) in a woman's blood, doctors were able to diagnose pre-eclampsia 2 days sooner on average.


" We knew monitoring PIGF was an accurate way to help detect the condition but were unsure whether making this tool available to clinicians would lead to better care for women. Now we know that it does," said the lead author.


Pre-eclampsia, a condition in pregnancy characterised by high blood pressure, sometimes with fluid retention and proteinuria, can cause damage to vital organs, fits and can be fatal for the woman and baby, if left untreated. Globally, 100 women die due to pre-eclampsia every day.


" For the last 100 years, we've diagnosed pre-eclampsia by measuring blood pressure and checking for protein in a woman's urine. These are relatively imprecise and often quite subjective, he noted.


For the study, the research team studies 1,035 women with suspected pre-eclampsia from 11 maternity units across UK. They're randomly assigned to 2 groups= 1 had their PIGF test results made available to their clinical team, the other did not.


The PIGF testing was shown to reduce the average time to diagnose pre-eclampsia from 4-2 days and serious complications before birth ( such as eclampsia, stroke and maternal death) to 4 % from 5 %.


There was no change in the likelihood of complications for the baby, the age at which babies were delivered prematurely or whether they're admitted to a neonatal unit, the researchers said.


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