Eye check-up for early detection Alzheimer's
A future non-invasive eye test may allow early detection of Alzheimer's disease before memory loss kicks in, say a team led by an
Indian-origin researcher.
Retina being an extension of the brain, the optical coherence tomography angiography (OCTA) will check patients' vision as well as brain health, said the study.
The researchers said that loss of blood vessels in retina would reflect changes in the brain, be it for both healthy people and Alzheimer's patients.
We know that there are changes that occur in the brain in the small blood vessels in people with Alzheimer's disease , and because the retina is an extension of the brain, we wanted to investigate whether these changes could be detected, said the lead author of the study.
Using OCTA that uses light waves that reveal blood flow in every layer of the retina, the researchers checked more than 200 people.
They found that in people with healthy brains, microscopic blood vessels form a dense web at the back of the eye inside retina- as was seen in 133 participants in a control group.
Conversely, in the eyes of 39 people with Alzheimer's disease, that web was less dense and even sparse in places.
The OCTA machines, relatively a new non-invasive technology, measures blood vessels that cannot be seen during a regular eye examination.
"It's possible that these changes in blood vessel density in the retina could mirror what's going on in the tiny blood vessels in the brain, perhaps before we're able to detect any changes in cognition", added an ophthalmologist.
Retina being an extension of the brain, the optical coherence tomography angiography (OCTA) will check patients' vision as well as brain health, said the study.
The researchers said that loss of blood vessels in retina would reflect changes in the brain, be it for both healthy people and Alzheimer's patients.
We know that there are changes that occur in the brain in the small blood vessels in people with Alzheimer's disease , and because the retina is an extension of the brain, we wanted to investigate whether these changes could be detected, said the lead author of the study.
Using OCTA that uses light waves that reveal blood flow in every layer of the retina, the researchers checked more than 200 people.
They found that in people with healthy brains, microscopic blood vessels form a dense web at the back of the eye inside retina- as was seen in 133 participants in a control group.
Conversely, in the eyes of 39 people with Alzheimer's disease, that web was less dense and even sparse in places.
The OCTA machines, relatively a new non-invasive technology, measures blood vessels that cannot be seen during a regular eye examination.
"It's possible that these changes in blood vessel density in the retina could mirror what's going on in the tiny blood vessels in the brain, perhaps before we're able to detect any changes in cognition", added an ophthalmologist.
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Labels: Alzheimer's disease, blood vessels, brain health, changes, early detection, non-invasive, optical coherence tomography angiography (OCTA), retina
posted by G S Iyer at 11:39 PM
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