The researchers removed the middle linking bone in the ossicular chain from three human cadavers and imaged the structures with CT. They employed an inexpensive 3D printer to create prostheses to restore continuity for each of the middle ears.

The prostheses were made from a resin that hardens when exposed to ultraviolet laser light. Each of the prostheses had unique measurements. Four surgeons then performed insertion of each prosthesis into each middle ear, blinded to the bone from and for which each was designed. The researchers then asked the surgeons to match each prosthesis to its correct source.

All four surgeons were able to correctly match the prosthesis model to its intended temporal bone - the bone containing the middle and inner parts of the ear.

The chances of this occurring randomly are 1 in 1,296, said a researcher.


"This study highlights the core strength of 3-D printing - the ability to very accurately reproduce anatomic relationships in space to a sub-millimetre level," he said. The results suggest that commercially available CT scanners can detect significant anatomic differences in normal human middle ear ossicles, and that these differences can be accurately represented with current 3D printing technology.

More significantly, surgeons are able to detect these differences, which should not only increase the likelihood of a proper fit, but also decrease surgical time, according to the researcher.

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