Promising New Treatment for Alzheimer's Disease

The brain sends electrical signals at different rates to activate and deactivate various functions within it, much like how traffic lights work. Gamma wave oscillations are the ones that influence cognitive processes and working memory – the type of memory that helps us remember phone numbers, for example – and Alzheimer's patients who experience symptoms such as memory impairment show a decrease in gamma wave oscillations in their brains.

In other studies, attempts were made to restore memory by increasing gamma wave oscillations with the help of external aids, such as magnetic frequencies, but without success. However, in the current study, there is a significant breakthrough. Instead of trying to influence gamma wave oscillations using external aids, the researchers decided to try to influence the brain from within – with the help of molecules – and the molecule DDL-920 succeeded in the task. 

 

In lab experiments, mice with Alzheimer's symptoms and healthy mice were tested, and they learned to navigate a maze with cues meant to lead them to the exit hole. The mice suffering from Alzheimer's were given a dose of the DDL-920 molecule twice a day for two weeks, and as a result, they showed remarkable improvement in their ability to navigate the maze and find the exit, functioning just as well as healthy mice in the same maze. 

 

Moreover, no negative side effects were observed from the treatment with the molecule, so researchers speculate that treatment with it will be safe for humans as well. However, more human trials are still needed to confirm this theory. If the trials show success at the same level, the molecule will allow effective treatments not only for Alzheimer's patients but also for those with schizophrenia, depression, and people on the autism spectrum.

Is this really a miracle cure for Alzheimer's? 

 

Dr. Módy claims that this mechanism has never been tested and studied before, so it represents a new direction that researchers have not yet tried, and it has a high chance of becoming the leading treatment for Alzheimer's patients. As mentioned, many more trials are still needed on the subject, but researchers are very optimistic. We hope to hear more developments on this soon, and we would be happy to discover if, in the near future, there will indeed be an available treatment that can restore the brain function of Alzheimer's patients to its former state. If so, we may be able to say goodbye to the damage caused by the disease and hello to a new era where "Alzheimer's" is no longer a scary word, but simply another disease that can be treated and its symptoms managed with a simple and quick treatment.

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