Pharmaceutical residues in fresh water pose a growing environmental risk
Over the past 20 years, concentrations of pharmaceuticals have
increased in freshwater sources all over the world, as research by
environmental experts has revealed. Levels of the
antibiotic ciprofloxacin have reached the point of potentially causing
damaging ecological effects. The research is the first to examine the
risks of two particular medicines in global freshwater sources. "The study calls for more widespread data gathering to measure the problem around the world."
"Getting an accurate picture of the environmental risks of
pharmaceuticals around the world depends on the availability of data,
which is limited," says lead author of the article. "It's
true that there are models, such as the ePiE model, which can give
detailed predictions of pharmaceutical concentrations in the
environment, but these are often only applicable to places where we
already have a lot of information, such as rivers in Europe." The new
model developed by the researchers, which builds on an existing model
with a lower resolution, makes it possible to come up with worldwide
predictions for individual ecoregions.
Damaging concentrations
For the two pharmaceuticals investigated in the study -
carbamazepine, an anti-epileptic drug, and ciprofloxacin, an antibiotic —
the environmental risks were found to be 10 to 20 times higher in 2015
than in 1995. The increased human use of ciprofloxacin was found to have
a particularly high impact globally. "The concentrations of this
antibiotic can be harmful for bacteria in the water, and these bacteria
in turn play an important role in various nutrient cycles," says the author. "Antibiotics can also have a negative impact on the
effectiveness of bacteria colonies used in wastewater treatment."
Antibiotic resistance as an environmental issue
Antibiotic resistance has been on the agenda of the World Health
Organization (WHO) and United Nations General Assembly for a few years
now. "Generally, it's seen as a problem for the health sector, as
resistant bacteria can be spread within hospitals or through livestock,"
says the author. "But there's little awareness of the role of the
environment in this problem, even though it becomes increasingly clear
that the environment functions as a source of resistance for various
pathogens."
More data in high-risk areas
"Our model predicts a relatively high environmental risk for
ecoregions in densely populated and dry areas such as the Middle East,
yet those are precisely the areas where there is little data on
pharmaceutical use and concentrations in surface waters," says the author. The researchers predicted human pharmaceutical consumption in
these areas using regression models based on consumption in other
countries, along with socio-economic and demographic information, and
linked this to information related to other factors such as water
sources and the number of people with access to wastewater treatment.
"Our model shows a particular need for new data in these types of
areas," says the author. "The model is really a starting point for
creating an insight into the environmental risks posed by
pharmaceuticals all over the world."
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Labels: environmental risk, fresh water, pharmaceutical residue
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