Why bereavement can lead to a ‘broken heart’

While loss of a loved one or breakdown of a relationship is often linked to a “broken heart”, not much is known why such emotional trauma could make someone physically ill. New research suggests that the body’s own immune response could play a key role in the condition. Symptoms of broken heart syndrome include shortness of breath and chest pain and as such it is often mistaken for a heart attack. However, unlike in a heart attack, patients do not suffer from a blockage of the arteries that supply the heart with blood. The cause of broken heart syndrome is not clearly understood but often is a result of intense emotional or physical trauma, which is thought to induce a strong response that affects the heart tissue. There is currently no treatment for broken heart syndrome, or Takotsubo cardiomyopathy.

The new study suggests that drugs that target inflammation could offer hope of fixing broken hearts. In the study, 55 patients with acute Takotsubo cardiomyopathy were recruited from five Scottish cardiac centres.

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