Wednesday, April 26, 2017

Dried Leaf Tablets Cured 18 Suffering From Drug-Resistant Malaria

18 patients suffering from malaria were reported ill in Congo. The report documents the experiences of patients in the North Kivu province of the Democratic Republic of Congo.

On not responding to the standard malaria medications they were put on a course of drugs made out of dried leaves of the Artemisia annua plant. 

These patients belonged to different age groups ranging from 14 months to 60 years and were reported to not have responded to the standard ACT treatment. 

"Successful treatment of all 18 artemisinin-based combination therapy (ACT)-resistant cases suggests that DLA (dried-leaf Artemisia) should be rapidly incorporated into the antimalarial regimen for Africa," the researchers said.


All patients showed symptoms of malaria and were originally treated with the recommended medication - artemisinin-based combination therapy (ACT). The therapy blends artemisinin, a chemical extract from Artemisia annua, with one or more other drugs that attack the malaria parasite in different ways.

The results, published in the journal Phytomedicine, suggest a new and inexpensive treatment option for the mosquito-borne disease that affects 212 million people worldwide.

 All were then treated with intravenously administered artesunate, the front-line medication for severe malaria, but again they showed no improvement. As a last resort, doctors turned to dried-leaf Artemisia, a therapy developed by Pamela Weathers, Professor at Worcester Polytechnic Institute (WPI) in Massachusetts, US. After five days of treatment with tablets made from only the dried and powered leaves of Artemisia, all 18 patients fully recovered, the study said. Laboratory tests showed they had no parasites remaining in their blood.


"These 18 patients were dying," Weathers said. "So to see 100 per cent recover, even the child who had lapsed into a coma, was just amazing. It's a small study, but the results are powerful," Weathers added. In 2015, the global tally of malaria reached 429,000 malaria deaths and 212 million new cases, according to the World Health Organization.

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