Monday, October 12, 2015

This gene can cure Parkinson's disease (PD), dementia, confirms study

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 Are you suffering from Parkinson's disease (PD) and dementia? If yes, then now is the time to deal with the syndrome with the help of scientists who have suggested that functional changes in an immune can regulate the gene and prevent the syndrome.

“It is discovered that non-inheritable PD may be caused by functional changes in the immune regulating gene Interferon-beta (IFNbeta),” according to research team at University of Copenhagen, Denmark.

However, they also revealed that in an experimental model of PD, the disease if treated with IFNbeta-gene therapy can successfully prevent neuronal death and disease effects.

According to the study, the human brain, which consists of approximately 100 billion neurons, can coordinate activities in all parts of the brain and play a vital role in keeping neurons healthy.
The study has been supported by data from Professor Shohreh Issazadeh-Navikas who has discovered that the immune gene IFNbeta plays a vital role in keeping neurons healthy.

They also found that the IFNbeta is essential for neurons ability to recycle waste proteins, which ultimately helps in lowering the waste proteins and prevents accumulation in disease-associated structures called Lewy bodies leading to the death of neurons.

The study was supported by a research done in mice which showed that body movement and restoration of memory can have developed disease and clinical signs similar to patients with PD and dementia with Lewy bodies (DLB).

Is your loved one also suffering from the disease? Check these symptoms:
Symptoms

  • Changes in memory, concentration and judgment
  • Trouble interpreting visual information
  • Muffled speech
  • Visual hallucinations
  • Delusions, especially paranoid ideas
  • Depression
  • Irritability and anxiety
  • Sleep disturbances, including excessive daytime drowsiness and rapid eye movement (REM) sleep disorder

Causes and risks
Certain factors at the time of Parkinson's diagnosis may increase future dementia risk, including older age, greater severity of motor symptoms, and having mild cognitive impairment (MCI).
Additional risk factors may include:

  • Hallucinations in a person who doesn't yet have other dementia symptoms
  • Excessive daytime sleepiness
  • Parkinson's symptom pattern known as postural instability and gait disturbance (PIGD), which includes "freezing" in mid-step, difficulty initiating movement, shuffling.

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